1. Fairley JA, Crowe TP, Fakhimi M, Palmer SJ, Greiner MA, Hellstein JW, Van Daele DJ, Messingham KN.  Disease endotypes predict severity of mucous membrand pemphigoid.  J Invest Dermatol. 2023 Mar 2:S0022-202X923)00108-2.  doi: 10.1016/j.jid.2023.02.012. Online ahead of print. PMID: 36870557
  2. Treco E, Huan E, Varzavand A, Fairley J, Messingham K. Elevated levels of sCD48 are inversely correlated with markers of disease activity in Bullous pemphigoid. J Exp Dermatol. 2022 Sep 22.  doi: 10.1111/exd.14679. Online ahead of print.  PMID: 36134505.
  3. Gourronc FA, Rebagliati MR, Kramer-Riesberg B, Fleck AM, Patten JJ, Geohegan-Barek K, Messingham KN, Davey RA, Maury W, Klingelhutz AJ. Adipocytes are susceptible to Ebola Virus infection. Virology. 2022 Aug;573:12-22. doi: 10.1016/j.virol.2022.05.007. Epub 2022 May 27. PubMed PMID: 35690007; PubMed Central PMCID: PMC9413353.
  4. Messingham KN, Cahill MP, Kilgore SH, Munjal A, Schlievert PM, Fairley JA. TSST-1+Staphylococcus aureus in Bullous Pemphigoid. J Invest Dermatol. 2022 Apr;142(4):1032-1039.e6. doi: 10.1016/j.jid.2021.08.438. Epub 2021 Oct 1. PubMed PMID: 34606884; PubMed Central PMCID: PMC9215375.
  5. Messingham KN, Crowe TP, Fairley JA. The Intersection of IgE Autoantibodies and Eosinophilia in the Pathogenesis of Bullous Pemphigoid. Front Immunol. 2019;10:2331. doi: 10.3389/fimmu.2019.02331. eCollection 2019. Review. PubMed PMID: 31636640; PubMed Central PMCID: PMC6787172.
  6. Stump M, Messingham KN, Fairley JA. Concurrent mucous membrane pemphigoid and membranous glomerulonephritis in a patient with autoantibodies targeting the 1080 region of collagen XVII. Br J Dermatol. 2019 Oct;181(4):835-836. doi: 10.1111/bjd.17923. Epub 2019 Jul 15. PubMed PMID: 30916378.
  7. Messingham KN, Miller AD, Narayanan NS, Connell SJ, Fairley JA. Demographics and Autoantibody Profiles of Pemphigoid Patients with Underlying Neurologic Diseases. J Invest Dermatol. 2019 Sep;139(9):1860-1866.e1. doi: 10.1016/j.jid.2019.01.034. Epub 2019 Mar 12. PubMed PMID: 30876802; PubMed Central PMCID: PMC6910721.
  8. Lin L, Hwang BJ, Culton DA, Li N, Burette S, Koller BH, Messingham KA, Fairley JA, Lee JJ, Hall RP, An L, Diaz LA, Liu Z. Eosinophils Mediate Tissue Injury in the Autoimmune Skin Disease Bullous Pemphigoid. J Invest Dermatol. 2018 May;138(5):1032-1043. doi: 10.1016/j.jid.2017.11.031. Epub 2017 Dec 12. PubMed PMID: 29246800; PubMed Central PMCID: PMC7531612.
  9. Scorza BM, Wacker MA, Messingham K, Kim P, Klingelhutz A, Fairley J, Wilson ME. Differential Activation of Human Keratinocytes by Leishmania Species Causing Localized or Disseminated Disease. J Invest Dermatol. 2017 Oct;137(10):2149-2156. doi: 10.1016/j.jid.2017.05.028. Epub 2017 Jun 22. PubMed PMID: 28647347; PubMed Central PMCID: PMC5786447.
  10. Messingham KN, Randall G, Fairley J. Exploring mechanisms of IgE-mediated autoimmunity through the lens of bullous pemphigoid. G Ital Dermatol Venereol. 2016 Apr;151(2):186-97. Epub 2016 Mar 9. Review. PubMed PMID: 26959553.
  11. Messingham KAN, Aust S, Helfenberger J, Parker KL, Schultz S, McKillip J, Narayanan NS, Fairley JA. Autoantibodies to Collagen XVII Are Present in Parkinson's Disease and Localize to Tyrosine-Hydroxylase Positive Neurons. J Invest Dermatol. 2016 Mar;136(3):721-723. doi: 10.1016/j.jid.2015.12.005. Epub 2015 Dec 14. PubMed PMID: 27015458; PubMed Central PMCID: PMC4809024.
  12. Messingham KN, Wang JW, Holahan HM, Srikantha R, Aust SC, Fairley JA. Eosinophil localization to the basement membrane zone is autoantibody- and complement-dependent in a human cryosection model of bullous pemphigoid. Exp Dermatol. 2016 Jan;25(1):50-5. doi: 10.1111/exd.12883. Epub 2015 Nov 23. PubMed PMID: 26475989; PubMed Central PMCID: PMC4730885.
  13. Messingham KN, Holahan HM, Frydman AS, Fullenkamp C, Srikantha R, Fairley JA. Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoid. PLoS One. 2014;9(9):e107725. doi: 10.1371/journal.pone.0107725. eCollection 2014. PubMed PMID: 25255430; PubMed Central PMCID: PMC4177878.
  14. Yu KK, Crew AB, Messingham KA, Fairley JA, Woodley DT. Omalizumab therapy for bullous pemphigoid. J Am Acad Dermatol. 2014 Sep;71(3):468-74. doi: 10.1016/j.jaad.2014.04.053. Epub 2014 Jun 20. PubMed PMID: 24954907; PubMed Central PMCID: PMC9215508.
  15. Messingham KA, Holahan HM, Fairley JA. Unraveling the significance of IgE autoantibodies in organ-specific autoimmunity: lessons learned from bullous pemphigoid. Immunol Res. 2014 Aug;59(1-3):273-8. doi: 10.1007/s12026-014-8547-7. Review. PubMed PMID: 24845463.
  16. Swick BL, Srikantha R, Messingham KN. Specific analysis of KIT and PDGFR-alpha expression and mutational status in Merkel cell carcinoma. J Cutan Pathol. 2013 Jul;40(7):623-30. doi: 10.1111/cup.12160. Epub 2013 Apr 29. PubMed PMID: 23621836.
  17. Fairley JA, Bream M, Fullenkamp C, Syrbu S, Chen M, Messingham KN. Missing the target: characterization of bullous pemphigoid patients who are negative using the BP180 enzyme-linked immunosorbant assay. J Am Acad Dermatol. 2013 Mar;68(3):395-403. doi: 10.1016/j.jaad.2012.09.012. Epub 2012 Oct 18. PubMed PMID: 23083837; PubMed Central PMCID: PMC5057577.
  18. Messingham KN, Pietras TA, Fairley JA. Role of IgE in bullous pemphigoid: a review and rationale for IgE directed therapies. G Ital Dermatol Venereol. 2012 Jun;147(3):251-7. Review. PubMed PMID: 22648326.
  19. Messingham KA, Onoh A, Vanderah EM, Giudice GJ, Fairley JA. Functional characterization of an IgE-class monoclonal antibody specific for the bullous pemphigoid autoantigen, BP180. Hybridoma (Larchmt). 2012 Apr;31(2):111-7. doi: 10.1089/hyb.2011.0102. PubMed PMID: 22509915; PubMed Central PMCID: PMC3326270.
  20. Messingham KN, Srikantha R, DeGueme AM, Fairley JA. FcR-independent effects of IgE and IgG autoantibodies in bullous pemphigoid. J Immunol. 2011 Jul 1;187(1):553-60. doi: 10.4049/jimmunol.1001753. Epub 2011 Jun 6. PubMed PMID: 21646296.
  21. Noe MH, Messingham KA, Brandt DS, Andrews JI, Fairley JA. Pregnant women have increased incidence of IgE autoantibodies reactive with the skin and placental antigen BP180 (type XVII collagen). J Reprod Immunol. 2010 Jun;85(2):198-204. doi: 10.1016/j.jri.2010.03.005. Epub 2010 May 14. PubMed PMID: 20471095; PubMed Central PMCID: PMC5242378.
  22. Messingham KA, Noe MH, Chapman MA, Giudice GJ, Fairley JA. A novel ELISA reveals high frequencies of BP180-specific IgE production in bullous pemphigoid. J Immunol Methods. 2009 Jul 31;346(1-2):18-25. doi: 10.1016/j.jim.2009.04.013. Epub 2009 May 5. PubMed PMID: 19422829; PubMed Central PMCID: PMC2703696.
  23. Fairley JA, Baum CL, Brandt DS, Messingham KA. Pathogenicity of IgE in autoimmunity: successful treatment of bullous pemphigoid with omalizumab. J Allergy Clin Immunol. 2009 Mar;123(3):704-5. doi: 10.1016/j.jaci.2008.11.035. Epub 2009 Jan 18. PubMed PMID: 19152970; PubMed Central PMCID: PMC4784096.
  24. Messingham KA, Badovinac VP, Jabbari A, Harty JT. A role for IFN-gamma from antigen-specific CD8+ T cells in protective immunity to Listeria monocytogenes. J Immunol. 2007 Aug 15;179(4):2457-66. doi: 10.4049/jimmunol.179.4.2457. PubMed PMID: 17675507.
  25. Messingham K, Harty JT. Adaptive Immunity to Listeria Monocytogenes. In: Shen H, Goldfine H, editors. Listeria monocytogenes Philadelphia, PA, USA: Springer; 2007. Chapter 11; p.225-251. 287p.
  26. Plackett TP, Colantoni A, Heinrich SA, Messingham KA, Gamelli RL, Kovacs EJ. The early acute phase response after burn injury in mice. J Burn Care Res. 2007 Jan-Feb;28(1):167-72. doi: 10.1097/BCR.0b013E31802CB84F. PubMed PMID: 17211221.
  27. Badovinac VP, Messingham KA, Griffith TS, Harty JT. TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells. J Immunol. 2006 Jul 15;177(2):999-1006. doi: 10.4049/jimmunol.177.2.999. PubMed PMID: 16818756.
  28. Badovinac VP, Messingham KA, Jabbari A, Haring JS, Harty JT. Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nat Med. 2005 Jul;11(7):748-56. doi: 10.1038/nm1257. Epub 2005 Jun 12. PubMed PMID: 15951824.
  29. Kovacs EJ, Faunce DE, Messingham KA. Ethanol and burn injury: estrogen modulation of immunity. Alcohol. 2004 Jul;33(3):209-16. doi: 10.1016/j.alcohol.2004.05.005. Review. PubMed PMID: 15596089.
  30. Hamilton SE, Porter BB, Messingham KA, Badovinac VP, Harty JT. MHC class Ia-restricted memory T cells inhibit expansion of a nonprotective MHC class Ib (H2-M3)-restricted memory response. Nat Immunol. 2004 Feb;5(2):159-68. doi: 10.1038/ni1026. Epub 2004 Jan 25. PubMed PMID: 14745446.
  31. Messingham KA, Badovinac VP, Harty JT. Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers. J Immunol. 2003 Oct 15;171(8):4254-62. doi: 10.4049/jimmunol.171.8.4254. PubMed PMID: 14530349.
  32. Badovinac VP, Messingham KA, Hamilton SE, Harty JT. Regulation of CD8+ T cells undergoing primary and secondary responses to infection in the same host. J Immunol. 2003 May 15;170(10):4933-42. doi: 10.4049/jimmunol.170.10.4933. PubMed PMID: 12734336.
  33. Heinrich SA, Messingham KA, Gregory MS, Colantoni A, Ferreira AM, Dipietro LA, Kovacs EJ. Elevated monocyte chemoattractant protein-1 levels following thermal injury precede monocyte recruitment to the wound site and are controlled, in part, by tumor necrosis factor-alpha. Wound Repair Regen. 2003 Mar-Apr;11(2):110-9. doi: 10.1046/j.1524-475x.2003.11206.x. PubMed PMID: 12631298.
  34. Messingham KA, Faunce DE, Kovacs EJ. Alcohol, injury, and cellular immunity. Alcohol. 2002 Nov;28(3):137-49. doi: 10.1016/s0741-8329(02)00278-1. Review. PubMed PMID: 12551755.
  35. Kovacs EJ, Messingham KA, Gregory MS. Estrogen regulation of immune responses after injury. Mol Cell Endocrinol. 2002 Jul 31;193(1-2):129-35. doi: 10.1016/s0303-7207(02)00106-5. Review. PubMed PMID: 12161012.
  36. Messingham KA, Heinrich SA, Schilling EM, Kovacs EJ. Interleukin-4 treatment restores cellular immunity after ethanol exposure and burn injury. Alcohol Clin Exp Res. 2002 Apr;26(4):519-26. PubMed PMID: 11981129.
  37. Kovacs EJ, Messingham KA. Influence of alcohol and gender on immune response. Alcohol Res Health. 2002;26(4):257-63. Review. PubMed PMID: 12875035; PubMed Central PMCID: PMC6676685.
  38. Messingham KA, Heinrich SA, Kovacs EJ. Estrogen restores cellular immunity in injured male mice via suppression of interleukin-6 production. J Leukoc Biol. 2001 Dec;70(6):887-95. PubMed PMID: 11739551.
  39. Messingham KA, Shirazi M, Duffner LA, Emanuele MA, Kovacs EJ. Testosterone receptor blockade restores cellular immunity in male mice after burn injury. J Endocrinol. 2001 May;169(2):299-308. doi: 10.1677/joe.0.1690299. PubMed PMID: 11312147.
  40. Durbin EA, Gregory MS, Messingham KA, Fontanilla CV, Duffner LA, Kovacs EJ. The role of interleukin 6 in interferon-gamma production in thermally injured mice. Cytokine. 2000 Nov;12(11):1669-75. doi: 10.1006/cyto.2000.0768. PubMed PMID: 11052818.
  41. Fontanilla CV, Faunce DE, Gregory MS, Messingham KA, Durbin EA, Duffner LA, Kovacs EJ. Anti-interleukin-6 antibody treatment restores cell-mediated immune function in mice with acute ethanol exposure before burn trauma. Alcohol Clin Exp Res. 2000 Sep;24(9):1392-9. PubMed PMID: 11003205.
  42. Colantoni A, Duffner LA, De Maria N, Fontanilla CV, Messingham KA, Van Thiel DH, Kovacs EJ. Dose-dependent effect of ethanol on hepatic oxidative stress and interleukin-6 production after burn injury in the mouse. Alcohol Clin Exp Res. 2000 Sep;24(9):1443-8. PubMed PMID: 11003212.
  43. Messingham KA, Fontanilla CV, Colantoni A, Duffner LA, Kovacs EJ. Cellular immunity after ethanol exposure and burn injury: dose and time dependence. Alcohol. 2000 Aug;22(1):35-44. doi: 10.1016/s0741-8329(00)00100-2. PubMed PMID: 11109026.
  44. Choudhry MA, Messingham KA, Namak S, Colantoni A, Fontanilla CV, Duffner LA, Sayeed MM, Kovacs EJ. Ethanol exacerbates T cell dysfunction after thermal injury. Alcohol. 2000 Jul;21(3):239-43. doi: 10.1016/s0741-8329(00)00093-8. PubMed PMID: 11091027.
  45. Young MR, Wright MA, Lathers DM, Messingham KA. Increased resistance to apoptosis by bone marrow CD34(+)progenitor cells from tumor-bearing mice. Int J Cancer. 1999 Aug 12;82(4):609-15. doi: 10.1002/(sici)1097-0215(19990812)82:4<609::aid-ijc23>3.0.co;2-a. PubMed PMID: 10404079.
  46. Wiers KM, Lozano Y, Messingham KA, Metz RJ, Young MR. 1alpha,25-dihydroxyvitamin D3 activates T cells of tumor bearers through protein phosphatase 2A. Cancer Immunol Immunother. 1997 Apr;44(2):97-102. doi: 10.1007/s002620050361. PubMed PMID: 9177471.
  47. Chou SH, Kojic LD, Messingham KN, Cunnic JE. Characterization of the effect of 2-deoxy-D-glucose(2-DG) on the immune system. Brain Behav Immun. 1996 Dec;10(4):399-416. doi: 10.1006/brbi.1996.0035. PubMed PMID: 9045754.